Based on the geographical location and climatic characteristics of Tianmen City, Hubei Province, the efficient and high quality cultivation model of watermelon and cauliflower intercropping with wheat was explored and summarized. Through rational crop sequencing, the model achieved orderly coordination of the three crops: wheat was sown from late October to early November and harvested in early to mid-May of the following year; watermelon was grafted and nursery-raised from late March to early April, transplanted in late April, and harvested from late June; cauliflower was nursery-raised in mid-July, transplanted in early to mid-August, and harvested in mid-to-late October. The key cultivation techniques for watermelon and cauliflower were emphasized. For watermelon cultivation, high quality disease resistant varieties (Lyushang, Meidu) were selected, and grafting using pumpkin rootstocks was adopted. Before transplanting, sufficient base fertilizer was applied, and ridging and film mulching were implemented. Vine management during wheat harvesting was coordinated to avoid damage. Two-vine pruning was applied, and vines were timely pressed. Irrigation and topdressing were carried out according to growth stages. For pest and disease control, agricultural methods (selecting resistant varieties, rational crop rotation), physical methods (hanging insect traps), and biological methods (spraying Bacillus thuringiensis) were prioritized, supplemented scientifically with low-toxicity chemical agents (25% azoxystrobin). Harvesting was conducted at the appropriate time, and field sanitation was maintained. For cauliflower cultivation, an efficient technology system centered on the “five modernizations” (intensive seedling raising, mechanized operations, integrated water-fertilizer management, green pest control, and post-harvest commercial handling) was adopted. Suitable disease-resistant varieties (Taisong 65 day) were selected, and intensive seedling raising in plug trays was implemented. Mechanized operations were applied for land preparation, ridging, and fertilization. Integrated water-fertilizer management was implemented during the growth period, and leaf folding for shading during the curd stage ensured quality. Green pest control principles were followed, combining agricultural, physical, and biological methods, supplemented with efficient and low-toxicity chemical agents (80% ethylicin, 25% azoxystrobin). Harvesting was performed when curds were compact, and straw was returned to the field. This model effectively improved the multiple cropping index and resource utilization efficiency, beneficial for the green and high quality development of agriculture.