To select high yield and high quality potato varieties suitable for cultivation in the eastern region of Liaoning Province, this experiment used the local main variety Favorita as the control, and selected 7 introduced varieties such as Zhongshu 321, Zhongshu 362, and Zhongshu 363 to conduct a comprehensive evaluation of the adaptability of the varieties (lines). The comprehensive performance of each variety, including phenological period, agronomic traits, yield and internal quality, was systematically analyzed. The results showed that the growth period of Longshu 30 was 83 days, making it a medium-to-early maturing variety. The plant height was 48.4 cm, with green stems, green leaves, white corollas, abundant flowers, high fruit setting rate, short creeping stems, a flat and round potato shape, yellow skin, light yellow flesh, shallow eyelets, the yield of the commodity grade was 85.3%, and a yield of 3 591.8 kg/667 m². The reducing sugar content was low and the protein content was high. Zhengcaishu No.11 had a growth period of 78 days and was a early maturing variety. Its plant height was 48.7 cm. The stems were purple, the leaves were green, the corolla was deep purple, the flowers were abundant, the yield rate was high, the creeping stems were short, the tubers were elliptical in shape, the skin was purple, the flesh was purple with a hint of white, the bud eyes were shallow, the commercial tuber rate was 83.9%, and the yield was 3 278.3 kg/667 m². The dry matter content was the highest, and the protein content was slightly higher than that of the control variety. In summary, Longshu 30 and Zhengcaishu No.11 had excellent comprehensive performance and can be further promoted for demonstration and cultivation.